换一批Antibody-mediated phagocytosis contributes to the anti-tumor activity of the therapeutic antibody daratumumab in lymphoma and multiple myeloma.
第一作者：
Marije B,Overdijk
第一单位：
a Genmab ; Utrecht , The Netherlands.
作者：
关键词
ADCC, antibody-dependent cellular cytotoxicityBL, Burkitt's lymphomaBM, bone marrowBurkitt's lymphomaCCS, cosmic calf serumCD38CDC, complement-dependent cytotoxicityDARA, daratumumabDP, double positiveE:T, effector to target ratioFcγR, Fc-gamma receptorIMiD, immunomodulatory drugMM, multiple myelomaMNC, mononuclear cellsM?, macrophagePBMC, peripheral blood mononuclear cellsdaratumumabmAb, monoclonal antibodymacrophagemultiple myelomaphagocytosistherapeutic antibody
医学主题词
动物(Animals);抗体, 单克隆(Antibodies, Monoclonal);抗体, 肿瘤(Antibodies, Neoplasm);细胞系, 肿瘤(Cell Line, Tumor);细胞吞噬作用(Cytophagocytosis);人类(Humans);淋巴瘤(Lymphoma);巨噬细胞(Macrophages);小鼠(Mice);多发性骨髓瘤(Multiple Myeloma);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)
DOI
10.1080/19420862.2015.1007813
PMID
25760767
发布时间
2024-03-24
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