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An evolutionarily conserved DNA architecture determines target specificity of the TWIST family bHLH transcription factors.

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第一作者： Andrew T,Chang

第一单位： Department of Pharmacology, University of California at San Diego, La Jolla, California, 92093, USA; The Biomedical Sciences Graduate Program, University of California at San Diego, La Jolla, California, 92093, USA;

作者： Andrew T,Chang ^[1] ; Yuanjie,Liu ^[2] ; Kasirajan,Ayyanathan ^[2] ; Chris,Benner ^[3] ; Yike,Jiang ^[4] ; Jeremy W,Prokop ^[5] ; Helicia,Paz ^[6] ; Dong,Wang ^[7] ; Hai-Ri,Li ^[7] ; Xiang-Dong,Fu ^[7] ; Frank J,Rauscher ^[8] ; Jing,Yang ^[9]

作者单位： Department of Pharmacology, University of California at San Diego, La Jolla, California, 92093, USA; The Biomedical Sciences Graduate Program, University of California at San Diego, La Jolla, California, 92093, USA; ^[1] The Wistar Institute, Philadelphia, Pennsylvania 19104, USA; ^[2] Salk Institute for Biological Studies, La Jolla, California 92037, USA; ^[3] Department of Pharmacology, University of California at San Diego, La Jolla, California, 92093, USA; The Biological Science Graduate Program, University of California at San Diego, La Jolla, California, 92093, USA; ^[4] Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA; ^[5] Department of Pharmacology, University of California at San Diego, La Jolla, California, 92093, USA; ^[6] Department of Cell and Molecular Medicine, University of California at San Diego, La Jolla, California, 92093, USA; ^[7] The Wistar Institute, Philadelphia, Pennsylvania 19104, USA; jingyang@ucsd.edu rauscher@wistar.org. ^[8] Department of Pharmacology, University of California at San Diego, La Jolla, California, 92093, USA; Department of Pediatrics, University of California at San Diego, La Jolla, California, 92093, USA jingyang@ucsd.edu rauscher@wistar.org. ^[9]

关键词 TWIST WR domain bHLH transcription factor epithelial–mesenchymal transition