换一批
换一批HMGB1-mediated autophagy modulates sensitivity of colorectal cancer cells to oxaliplatin via MEK/ERK signaling pathway.
作者：
关键词
3-MA, 3-methyladenosine5-FU, 5-fluorouracilCCK8, Cell Counting Kit-8CRC, Colorectal cancerERK, extracellular signal-regulated kinaseHMGB1HMGB1, High–mobility group box 1 proteinMEK, extracellular signal-regulated kinase kinaseMEK/ERK pathwayapoptosisautophagycolorectal canceroxaliplatinshRNA, short hairpin RNA
主题词
细胞凋亡(Apoptosis);自噬(Autophagy);细胞系, 肿瘤(Cell Line, Tumor);结直肠肿瘤(Colorectal Neoplasms);抗药性, 肿瘤(Drug Resistance, Neoplasm);细胞外信号调节MAP激酶类(Extracellular Signal-Regulated MAP Kinases);HCT116细胞(HCT116 Cells);HMGB1蛋白质(HMGB1 Protein);HT29细胞(HT29 Cells);人类(Humans);MAP激酶信号系统(MAP Kinase Signaling System);有机铂化合物(Organoplatinum Compounds);磷酰化(Phosphorylation);信号传导(Signal Transduction)
DOI
10.1080/15384047.2015.1017691
PMID
25778491
发布时间
2021-09-10
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