AcpM, the meromycolate extension acyl carrier protein of Mycobacterium tuberculosis, is activated by the 4'-phosphopantetheinyl transferase PptT, a potential target of the multistep mycolic acid biosynthesis.
第一作者:
Oren,Zimhony
第一单位:
†Kaplan Medical Center, Affiliated to the School of Medicine, Hebrew University of Jerusalem and Hadassah Medical Center, POB1 Rehovot 76100, Israel.
作者:
主题词
氨基酸序列(Amino Acid Sequence);细菌蛋白质类(Bacterial Proteins);载体蛋白质类(Carrier Proteins);辅酶A(Coenzyme A);酶激活(Enzyme Activation);模型, 分子(Models, Molecular);分子序列数据(Molecular Sequence Data);牛分枝杆菌(Mycobacterium bovis);结核分枝杆菌(Mycobacterium tuberculosis);分枝菌酸(Mycolic Acids);肽合酶类(Peptide Synthases);蛋白质结合(Protein Binding);重组蛋白质类(Recombinant Proteins);转移酶类(其他取代磷酸族)(Transferases (Other Substituted Phosphate Groups))
DOI
10.1021/bi501444e
PMID
25785780
发布时间
2015-04-14
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Biochemistry
2360-71页
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