首页> Gene therapy> Intravaginal HPV DNA vaccination with electroporation induces local CD8+ T-cell immune responses and antitumor effects against cervicovaginal tumors.

Intravaginal HPV DNA vaccination with electroporation induces local CD8+ T-cell immune responses and antitumor effects against cervicovaginal tumors.

导出 OA

翻译打印收藏纠错

第一作者： Y,Sun

第一单位： 1] Department of Obstetrics and Gynecology, Shanghai First People's Hospital, Shanghai Jiao Tong University, Shanghai, China [2] Departments of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA.

作者： Y,Sun ^[1] ; S,Peng ^[2] ; J,Qiu ^[3] ; J,Miao ^[4] ; B,Yang ^[2] ; J,Jeang ^[2] ; C-F,Hung ^[5] ; T-C,Wu ^[6]

作者单位： 1] Department of Obstetrics and Gynecology, Shanghai First People's Hospital, Shanghai Jiao Tong University, Shanghai, China [2] Departments of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA. ^[1] Departments of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA. ^[2] 1] Departments of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA [2] Department of Obstetrics and Gynecology, Shanghai Tenth People's Hospital of Tongji University Shanghai, Shanghai, China. ^[3] 1] Departments of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA [2] Department of General Surgery, The Second Hospital of Dalian Medical University, Dalian, Liaoning, China [3] Department of Hepatobiliary and Pancreatic Surgery, The Second Hospital of Dalian Medical University, Dalian, Liaoning, China. ^[4] 1] Departments of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA [2] Department of Oncology, Johns Hopkins Medical Institutions, Baltimore, MD, USA. ^[5] 1] Departments of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA [2] Department of Oncology, Johns Hopkins Medical Institutions, Baltimore, MD, USA [3] Department of Obstetrics and Gynecology, Johns Hopkins Medical Institutions, Baltimore, MD, USA [4] Department of Molecular Microbiology and Immunology, Johns Hopkins Medical Institutions, Baltimore, MD, USA. ^[6]

医学主题词投药, 阴道内(Administration, Intravaginal);动物(Animals);抗肿瘤药(Antineoplastic Agents);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);细胞系, 肿瘤(Cell Line, Tumor);电穿孔(Electroporation);女(雌)性(Female);小鼠, 近交C57BL(Mice, Inbred C57BL);乳头状瘤病毒疫苗(Papillomavirus Vaccines);宫颈肿瘤(Uterine Cervical Neoplasms);疫苗, DNA(Vaccines, DNA)

DOI 10.1038/gt.2015.17

PMID 25786869

发布时间 2024-05-16

基金项目

R01 CA114425/CA/NCI NIH HHS/United States P20 CA192988/CA/NCI NIH HHS/United States R21 CA178255/CA/NCI NIH HHS/United States P50 CA098252/CA/NCI NIH HHS/United States 2R01CA114425-06/CA/NCI NIH HHS/United States 5R21CA178255-02/CA/NCI NIH HHS/United States P50CA098252/CA/NCI NIH HHS/United States

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交