Trabectedin monotherapy after standard chemotherapy versus best supportive care in patients with advanced, translocation-related sarcoma: a randomised, open-label, phase 2 study.

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作者： Akira,Kawai ^[1] ; Nobuhito,Araki ^[2] ; Hideshi,Sugiura ^[3] ; Takafumi,Ueda ^[4] ; Tsukasa,Yonemoto ^[5] ; Mitsuru,Takahashi ^[6] ; Hideo,Morioka ^[7] ; Hiroaki,Hiraga ^[8] ; Toru,Hiruma ^[9] ; Toshiyuki,Kunisada ^[10] ; Akihiko,Matsumine ^[11] ; Takanori,Tanase ^[12] ; Tadashi,Hasegawa ^[13] ; Shunji,Takahashi ^[14]

作者单位： Division of Musculoskeletal Oncology, National Cancer Center Hospital, Tokyo, Japan. Electronic address: akawai@ncc.go.jp. ^[1] Department of Orthopaedic Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan. ^[2] Department of Orthopaedic Surgery, Aichi Cancer Center Hospital, Aichi, Japan. ^[3] Department of Orthopaedic Surgery, Osaka National Hospital, Osaka, Japan. ^[4] Division of Orthopaedic Surgery, Chiba Cancer Center, Chiba, Japan. ^[5] Division of Orthopaedic Surgery, Shizuoka Cancer Center Hospital, Shizuoka, Japan. ^[6] Department of Orthopaedic Surgery, School of Medicine, Keio University, Tokyo, Japan. ^[7] Department of Orthopaedic Surgery, Hokkaido Cancer Center, Hokkaido, Japan. ^[8] Department of Musculoskeletal Tumor Surgery, Kanagawa Cancer Center, Kanagawa, Japan. ^[9] Department of Medical Materials for Musculoskeletal Reconstruction, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan. ^[10] Department of Orthopedic Surgery, Mie University Graduate School of Medicine, Mie, Japan. ^[11] Department of Data Science, Taiho Parmaceutical Co., Ltd, Tokyo, Japan. ^[12] Department of Surgical Pathology, Sapporo Medical University School of Medicine, Hokkaido, Japan. ^[13] Department of Medical Oncology, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan. ^[14]