Donor Lymphocyte Infusions for Chronic Myeloid Leukemia Relapsing after Allogeneic Stem Cell Transplantation: May We Predict Graft-versus-Leukemia Without Graft-versus-Host Disease?

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作者： Aleksandar,Radujkovic ^[1] ; Cesare,Guglielmi ^[2] ; Stefania,Bergantini ^[2] ; Simona,Iacobelli ^[3] ; Anja,van Biezen ^[4] ; Dragana,Milojkovic ^[5] ; Alois,Gratwohl ^[6] ; Antonius V M B,Schattenberg ^[7] ; Leo F,Verdonck ^[8] ; Dietger W,Niederwieser ^[9] ; Theo,de Witte ^[10] ; Nicolaus,Kröger ^[11] ; Eduardo,Olavarria ^[12] ; Chronic Malignancies Working Party of the European Society for Blood and Marrow Transplantation

作者单位： Department of Internal Medicine V, University Hospital Heidelberg, Heidelberg, Germany. Electronic address: aleksandar.radujkovic@med.uni-heidelberg.de. ^[1] Dipartimento di Medicina Clinica e Molecolare, Università "Sapienza", Rome, Italy. ^[2] University of Rome Tor Vergata, Centro Interdipartimentale di Biostatistica e Bioinformatica (CIBB), Rome, Italy. ^[3] Department of Medical Statistics and Bioinformatics, Leiden University, Leiden, The Netherlands. ^[4] Department of Haematology, Hammersmith Hospitals Trust, Imperial College London, London, United Kingdom. ^[5] Department of Hematology, University Hospital Basel, Basel, Switzerland. ^[6] Department of Hematology, Radboud University Medical Center, Nijmegen, The Netherlands. ^[7] Department of Haematology, University Medical Center Utrecht, Utrecht, The Netherlands. ^[8] Department of Hematology/Oncology, University of Leipzig, Leipzig, Germany. ^[9] Department of Tumor Immunology, Radboud University Medical Center, Nijmegen, The Netherlands. ^[10] Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. ^[11] Complejo Hospitalario de Navarra, Pamplona, Spain. ^[12]

关键词 Allogeneic stem cell transplantation Chronic myeloid leukemia Donor lymphocyte infusions Graft-versus-host disease Graft-versus-leukemia Relapse