CDK2 Inhibition Causes Anaphase Catastrophe in Lung Cancer through the Centrosomal Protein CP110.

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作者： Shanhu,Hu ^[1] ; Alexey V,Danilov ^[2] ; Kristina,Godek ^[3] ; Bernardo,Orr ^[3] ; Laura J,Tafe ^[4] ; Jaime,Rodriguez-Canales ^[5] ; Carmen,Behrens ^[5] ; Barbara,Mino ^[5] ; Cesar A,Moran ^[6] ; Vincent A,Memoli ^[7] ; Lisa Maria,Mustachio ^[1] ; Fabrizio,Galimberti ^[1] ; Saranya,Ravi ^[1] ; Andrew,DeCastro ^[1] ; Yun,Lu ^[1] ; David,Sekula ^[1] ; Angeline S,Andrew ^[8] ; Ignacio I,Wistuba ^[5] ; Sarah,Freemantle ^[1] ; Duane A,Compton ^[3] ; Ethan,Dmitrovsky ^[9]

作者单位： Department of Pharmacology and Toxicology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire. Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire. ^[1] Department of Medicine, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire. The Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire. Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire. ^[2] Department of Biochemistry, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire. The Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire. Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire. ^[3] Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire. Department of Pathology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire. ^[4] Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas. ^[5] Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas. ^[6] The Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire. Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire. Department of Pathology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire. ^[7] The Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire. Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire. Department of Community and Family Medicine, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire. ^[8] Department of Pharmacology and Toxicology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire. Department of Medicine, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire. The Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire. Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire. ethan.dmitrovsky@dartmouth.edu. ^[9]