Upregulation of NKG2C+ natural killer cells, TLR-2 expression on monocytes and downregulation of regulatory T-cells influence PEG-IFN treatment efficacy in entecavir-suppressed patients with CHB.
第一作者:
Weiming,Yan
第一单位:
Department and Institute of Infectious Disease, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
作者:
主题词
抗病毒药(Antiviral Agents);用药计划表(Drug Administration Schedule);基因表达调控(Gene Expression Regulation);鸟嘌呤(Guanine);乙型肝炎表面抗原(Hepatitis B Surface Antigens);乙型肝炎e抗原(Hepatitis B e Antigens);乙型肝炎病毒(Hepatitis B virus);乙型肝炎, 慢性(Hepatitis B, Chronic);宿主与病原体相互作用(Host-Pathogen Interactions);人类(Humans);干扰素α(Interferon-alpha);杀伤细胞, 天然(Killer Cells, Natural);单核细胞(Monocytes);NK细胞凝集素样受体亚家族C(NK Cell Lectin-Like Receptor Subfamily C);聚乙烯二醇类(Polyethylene Glycols);重组蛋白质类(Recombinant Proteins);信号传导(Signal Transduction);T淋巴细胞, 调节性(T-Lymphocytes, Regulatory);Toll样受体2(Toll-Like Receptor 2);治疗结果(Treatment Outcome)
DOI
10.3851/IMP2953
PMID
25814467
发布时间
2018-12-02
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Antiviral therapy
591-602页
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