Licochalcone F alleviates glucose tolerance and chronic inflammation in diet-induced obese mice through Akt and p38 MAPK.

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第一作者： Eun-Jung,Bak

第一单位： Oral Cancer Research Institute, Yonsei University College of Dentistry, Seoul, South Korea.

作者： Eun-Jung,Bak ^[1] ; Kyung-Chul,Choi ^[2] ; Sungil,Jang ^[3] ; Gye-Hyeong,Woo ^[4] ; Ho-Geun,Yoon ^[5] ; Younghwa,Na ^[6] ; Yun-Jung,Yoo ^[7] ; Youngseok,Lee ^[8] ; Yangsik,Jeong ^[9] ; Jeong-Heon,Cha ^[10]

作者单位： Oral Cancer Research Institute, Yonsei University College of Dentistry, Seoul, South Korea. ^[1] Department of Biomedical Sciences, University of Ulsan College of Medicine, Seoul, South Korea. ^[2] BK21 PLUS Project, Yonsei University College of Dentistry, South Korea; Department of Oral Biology, Yonsei University College of Dentistry, Seoul, South Korea; Department of Applied Life Science, The Graduate School, Yonsei University, Seoul, South Korea. ^[3] Department of Clinical Laboratory Science, Semyung University, Jecheon, South Korea. ^[4] Department of Biochemistry and Molecular Biology, Center for Chronic Metabolic Disease Research, College of Medicine, Yonsei University, Seoul, South Korea. ^[5] College of Pharmacy, CHA University, Seoul, South Korea. ^[6] Department of Oral Biology, Yonsei University College of Dentistry, Seoul, South Korea; Department of Applied Life Science, The Graduate School, Yonsei University, Seoul, South Korea. ^[7] Department of Bio and Fermentation Convergence Technology, Kookmin University, Seoul, South Korea. ^[8] Department of Biochemistry, Yonsei University Wonju College of Medicine, Wonju, South Korea. Electronic address: yjeong@yonsei.ac.kr. ^[9] Oral Cancer Research Institute, Yonsei University College of Dentistry, Seoul, South Korea; BK21 PLUS Project, Yonsei University College of Dentistry, South Korea; Department of Oral Biology, Yonsei University College of Dentistry, Seoul, South Korea; Department of Applied Life Science, The Graduate School, Yonsei University, Seoul, South Korea. Electronic address: Jcha@yuhs.ac. ^[10]

关键词 Anti-inflammatory effect Diet-induced obese mice Licochalcone F Obesity-induced chronic inflammation