换一批
换一批Shiga toxins induce autophagic cell death in intestinal epithelial cells via the endoplasmic reticulum stress pathway.
作者：
关键词
3-MA, 3-methyladenineAO, acridine orangeATF4, activating transcription factor 4ATG, autophagy-relatedBECN1, Beclin 1, autophagy-relatedBaf A1, bafilomycin A1CASP3, caspase 3, apoptosis-related cysteine peptidaseDDIT3, DNA-damage-inducible transcript 3E. coli O157:H7EHEC O157, Escherichia coli O157:H7ER stressFACS, fluorescence activated cell sortingMAP1LC3B, microtubule-associated protein 1 light chain 3 betaMAPK, mitogen-activated protein kinaseMDC, monodansylcadaverineNUPR1, nuclear protein, transcriptional regulator, 1PARP1, poly (ADP-ribose) polymerase 1PBS, phosphate-buffered salinePI, propidium iodideShiga toxinsStxs, Shiga toxinsTEM, transmission electron microscopyTRIB3, tribbles pseudokinase 3Thap, thapsigarginWT, wild typeZ-VAD, Z-VAD-FMKautophagic cell deathautophagyΔ, knockout
主题词
动物(Animals);细胞凋亡(Apoptosis);自噬(Autophagy);细胞死亡(Cell Death);细胞, 培养的(Cells, Cultured);上皮细胞(Epithelial Cells);大肠杆菌(Escherichia coli);人类(Humans);小鼠, 近交C57BL(Mice, Inbred C57BL);志贺毒素类(Shiga Toxins);转录因子CHOP(Transcription Factor CHOP)
DOI
10.1080/15548627.2015.1023682
PMID
25831014
发布时间
2018-11-13
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Autophagy
344-54页
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