SKP2 is a direct transcriptional target of MYCN and a potential therapeutic target in neuroblastoma.
作者:
主题词
细胞凋亡(Apoptosis);结合部位(Binding Sites);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);E盒元件(E-Box Elements);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);基因, 报告(Genes, Reporter);人类(Humans);突变(Mutation);神经母细胞瘤(Neuroblastoma);核蛋白质类(Nuclear Proteins);癌基因蛋白质类(Oncogene Proteins);启动区, 遗传(Promoter Regions, Genetic);RNA干扰(RNA Interference);RNA, 信使(RNA, Messenger);S期激酶相关蛋白质类(S-Phase Kinase-Associated Proteins);时间因素(Time Factors);转录, 遗传(Transcription, Genetic);转染(Transfection)
DOI
10.1016/j.canlet.2015.03.044
PMID
25843293
发布时间
2024-02-10
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Cancer letters
37-45页
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