Islet β-cell failure in type 2 diabetes--Within the network of toxic lipids.

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作者： Justyna,Janikiewicz ^[1] ; Katarzyna,Hanzelka ^[1] ; Kamil,Kozinski ^[1] ; Katarzyna,Kolczynska ^[1] ; Agnieszka,Dobrzyn ^[2]

作者单位： Laboratory of Cell Signaling and Metabolic Disorders, Nencki Institute of Experimental Biology, PAS, Warsaw, Poland. ^[1] Laboratory of Cell Signaling and Metabolic Disorders, Nencki Institute of Experimental Biology, PAS, Warsaw, Poland. Electronic address: adobrzyn@nencki.gov.pl. ^[2]

关键词 Autophagy Endoplasmic reticulum stress Fatty acid-induced toxicity Mitochondrial dysfunction Pancreatic β-cell Type 2 diabetes mellitus

主题词自噬(Autophagy);神经酰胺类(Ceramides);糖尿病, 2型(Diabetes Mellitus, Type 2);内质网(Endoplasmic Reticulum);人类(Humans);胰岛(Islets of Langerhans);线粒体(Mitochondria)

DOI 10.1016/j.bbrc.2015.03.153

PMID 25843796

发布时间 2022-03-10

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