BMPR2 preserves mitochondrial function and DNA during reoxygenation to promote endothelial cell survival and reverse pulmonary hypertension.
第一作者:
Isabel,Diebold
第一单位:
Department of Pediatrics and Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA; The Vera Moulton Wall Center for Pulmonary Vascular Disease, Stanford University School of Medicine, Stanford, CA 94305, USA.
作者:
医学主题词
方差分析(Analysis of Variance);动物(Animals);印迹法, 蛋白质(Blotting, Western);骨形态发生蛋白受体, Ⅱ型(Bone Morphogenetic Protein Receptors, Type II);细胞存活(Cell Survival);DNA(DNA);DNA引物(DNA Primers);内皮细胞(Endothelial Cells);流式细胞术(Flow Cytometry);荧光抗体技术(Fluorescent Antibody Technique);HEK293细胞(HEK293 Cells);人类(Humans);高血压, 肺性(Hypertension, Pulmonary);膜电位, 线粒体(Membrane Potential, Mitochondrial);小鼠(Mice);线粒体(Mitochondria);模型, 生物学(Models, Biological);聚合酶链反应(Polymerase Chain Reaction);肺动脉(Pulmonary Artery);RNA, 小分子干扰(RNA, Small Interfering);再生(Regeneration)
DOI
10.1016/j.cmet.2015.03.010
PMID
25863249
发布时间
2020-01-31
- 浏览2
Cell metabolism
596-608页
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