换一批Belinostat, a potent HDACi, exerts antileukaemic effect in human acute promyelocytic leukaemia cells via chromatin remodelling.
第一作者：
Giedre,Valiuliene
第一单位：
Department of Molecular Cell Biology, Institute of Biochemistry, Vilnius University, Vilnius, Lithuania.
作者：
医学主题词
乙酰化作用(Acetylation);细胞分化(Cell Differentiation);细胞存活(Cell Survival);染色质组装和分解(Chromatin Assembly and Disassembly);周期素依赖激酶抑制剂p27(Cyclin-Dependent Kinase Inhibitor p27);DNA甲基化(DNA Methylation);基因表达调控, 白血病(Gene Expression Regulation, Leukemic);粒细胞(Granulocytes);HL-60细胞(HL-60 Cells);组蛋白脱乙酰基酶抑制剂(Histone Deacetylase Inhibitors);组蛋白类(Histones);人类(Humans);羟肟酸类(Hydroxamic Acids);白血病, 早幼粒细胞, 急性(Leukemia, Promyelocytic, Acute);分子序列数据(Molecular Sequence Data);肿瘤蛋白质类(Neoplasm Proteins);启动区, 遗传(Promoter Regions, Genetic);磺胺类(Sulfonamides);维甲酸(Tretinoin)
DOI
10.1111/jcmm.12550
PMID
25864732
发布时间
2018-11-13
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