A validated LC-MS/MS assay for quantification of 24(S)-hydroxycholesterol in plasma and cerebrospinal fluid.

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第一作者： Rohini,Sidhu

第一单位： Diabetic Cardiovascular Disease Center, Washington University School of Medicine, St. Louis, MO 63110.

作者： Rohini,Sidhu ^[1] ; Hui,Jiang ^[1] ; Nicole Y,Farhat ^[2] ; Nuria,Carrillo-Carrasco ^[3] ; Myra,Woolery ^[4] ; Elizabeth,Ottinger ^[5] ; Forbes D,Porter ^[2] ; Jean E,Schaffer ^[1] ; Daniel S,Ory ^[1] ; Xuntian,Jiang ^[1]

作者单位： Diabetic Cardiovascular Disease Center, Washington University School of Medicine, St. Louis, MO 63110. ^[1] Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892. ^[2] Therapeutics for Rare and Neglected Diseases National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850. ^[3] Nursing Department, National Institutes of Health, Bethesda, MD 20892. ^[4] Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850. ^[5]

关键词 2-hydroxypropyl-β-cyclodextrin Niemann-Pick C1 disease two-dimensional liquid chromatography-tandem mass spectrometry validation