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Mining disease genes using integrated protein-protein interaction and gene-gene co-regulation information.

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第一作者： Jin,Li

第一单位： School of Computer Science and Technology, Harbin Institute of Technology, Harbin, Heilongjiang, China ; School of Life Science and Technology, Harbin Institute of Technology, Harbin, Heilongjiang, China ; College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang, China.

作者： Jin,Li ^[1] ; Limei,Wang ^[2] ; Maozu,Guo ^[3] ; Ruijie,Zhang ^[4] ; Qiguo,Dai ^[3] ; Xiaoyan,Liu ^[3] ; Chunyu,Wang ^[3] ; Zhixia,Teng ^[3] ; Ping,Xuan ^[3] ; Mingming,Zhang ^[4]

作者单位： School of Computer Science and Technology, Harbin Institute of Technology, Harbin, Heilongjiang, China ; School of Life Science and Technology, Harbin Institute of Technology, Harbin, Heilongjiang, China ; College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang, China. ^[1] College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang, China ; School of Basic Medical Sciences, Harbin Medical University, Harbin, Heilongjiang, China. ^[2] School of Computer Science and Technology, Harbin Institute of Technology, Harbin, Heilongjiang, China. ^[3] College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang, China. ^[4]

关键词 AD, Alzheimer disease Co-regulation network Disease gene mining GGCRN, gene–gene co-regulation network HPRD, Human Protein Reference Database KEGG, Kyoto Encyclopedia of Genes and Genomes PPI, protein–protein interaction Protein–protein interaction RWR, random walk with restart Random walk with restart SNP, single-nucleotide polymorphism eQTL eQTLs, expression quantitative trait loci

DOI 10.1016/j.fob.2015.03.011

PMID 25870785

发布时间 2018-11-13

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