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Convergent mutations and kinase fusions lead to oncogenic STAT3 activation in anaplastic large cell lymphoma.

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第一作者: Ramona,Crescenzo
第一单位: Department of Molecular Biotechnology and Health Science and Center for Experimental Research and Medical Studies, University of Torino, 10126 Torino, Italy; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10021, USA.
作者单位: Department of Molecular Biotechnology and Health Science and Center for Experimental Research and Medical Studies, University of Torino, 10126 Torino, Italy; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10021, USA. [1] Department of Molecular Biotechnology and Health Science and Center for Experimental Research and Medical Studies, University of Torino, 10126 Torino, Italy; Department of Control and Computer Engineering, Politecnico di Torino, 10129 Torino, Italy; Department of Biomedical Informatics and Department of Systems Biology, Center for Computational Biology and Bioinformatics, Columbia University, New York, NY 10027, USA. [2] Department of Molecular Biotechnology and Health Science and Center for Experimental Research and Medical Studies, University of Torino, 10126 Torino, Italy. [3] Department of Control and Computer Engineering, Politecnico di Torino, 10129 Torino, Italy. [4] Department of Pathology, A.O. Città della Salute e della Scienza (Molinette), 10126 Torino, Italy. [5] Lymphoma and Genomics Research Program, Institute of Oncology Research, 6500 Bellinzona, Switzerland. [6] Translational Cell and Tissue Research Lab, KU Leuven, 3000 Leuven, Belgium. [7] Institute of Pathology, University of Würzburg and Comprehensive Cancer Center Mainfranken, 97080 Würzburg, Germany. [8] Ludwing Boltzmann Institute for Cancer Research, 1090 Vienna, Austria. [9] Research Unit Dermatopathology of the Medical University of Graz, 8036 Graz, Austria. [10] Institute of Pathology, University Hospital Basel, 4031 Basel, Switzerland. [11] Pathology & Lymphoid Malignancies Units, San Raffaele Scientific Institute, 20132 Milan, Italy. [12] Department of Human Pathology, University of Pavia and Scientific Institute Fondazione Policlinico San Matteo, 27100 Pavia, Italy. [13] Department of Pathology, City of Hope Medical Center, Duarte, CA 91010, USA. [14] Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198, USA. [15] Cancer Genomics, Instituto de Formación e Investigación Marqués de Valdecilla and Department of Pathology, Hospital Universitario Marqués de Valdecilla, 39008 Santander, Spain. [16] Department of Pathology and Diagnostics, University of Verona, 37134 Verona, Italy. [17] Division of Hematology, Department of Translational Medicine, Amedeo Avogadro University of Eastern Piedmont, 28100 Novara, Italy. [18] European Institute of Oncology, 20141 Milano, Italy; Bologna University School of Medicine, 40126 Bologna, Italy. [19] Institute of Hematology-Centro di Ricerche Onco-Ematologiche (CREO), Ospedale S. Maria della Misericordia, University of Perugia, 06100 Perugia, Italy. [20] The Jackson Laboratory, Bar Harbor, ME 04609, USA. [21] Janssen Research & Development, a Division of Janssen-Cilag, Campus de Maigremont, CS10615, 27106 Val-de-Reuil Cedex, France. [22] Janssen Research & Development, a Division of Janssen Pharmaceutica NV, Turnhoutseweg 30, 2340 Beerse, Belgium. [23] Department of Molecular Biotechnology and Health Science and Center for Experimental Research and Medical Studies, University of Torino, 10126 Torino, Italy; Department of Pathology and NYU Cancer Center, New York University School of Medicine, New York, NY 10016, USA. [24] Lymphoma and Genomics Research Program, Institute of Oncology Research, 6500 Bellinzona, Switzerland; Oncology Institute of Southern Switzerland, 6500 Bellinzona, Switzerland. [25] Department of Biomedical Informatics and Department of Systems Biology, Center for Computational Biology and Bioinformatics, Columbia University, New York, NY 10027, USA. Electronic address: rr2579@cumc.columbia.edu. [26] Department of Molecular Biotechnology and Health Science and Center for Experimental Research and Medical Studies, University of Torino, 10126 Torino, Italy; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10021, USA; Department of Pathology and NYU Cancer Center, New York University School of Medicine, New York, NY 10016, USA. Electronic address: ggi9001@med.cornell.edu. [27]
DOI 10.1016/j.ccell.2015.03.006
PMID 25873174
发布时间 2023-08-16
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