Berberine alleviates ox-LDL induced inflammatory factors by up-regulation of autophagy via AMPK/mTOR signaling pathway.

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作者： Xiaodi,Fan ^[1] ; Jun,Wang ^[2] ; Jincai,Hou ^[3] ; Chengren,Lin ^[4] ; Alan,Bensoussan ^[5] ; Dennis,Chang ^[6] ; Jianxun,Liu ^[7] ; Bing,Wang ^[8]

作者单位： Department of Tianjin, University of Traditional Chinese Medicine, Tianjin, 300193, China. fanxdfanxd@126.com. ^[1] Department of Experimental Research Center, Xiyuan Hospital of China Academy of Chinese Medical Sciences, 1 Xiyuan Caochang, Hai Dian District, Beijing, 100091, China. fanxdfanxd@126.com. ^[2] Institute of Basic Theory, China Academy of Chinese Medical Sciences, Beijing, 100700, China. maggie.wj@126.com. ^[3] Department of Experimental Research Center, Xiyuan Hospital of China Academy of Chinese Medical Sciences, 1 Xiyuan Caochang, Hai Dian District, Beijing, 100091, China. houjchoujc@126.com. ^[4] Department of Experimental Research Center, Xiyuan Hospital of China Academy of Chinese Medical Sciences, 1 Xiyuan Caochang, Hai Dian District, Beijing, 100091, China. lincrlincr@126.com. ^[5] Centre for Complementary Medicine Research, School of Science and Health, University of Western Sydney, Parramatta, NSW, 2751, Australia. wang_liru2009@126.com. ^[6] Centre for Complementary Medicine Research, School of Science and Health, University of Western Sydney, Parramatta, NSW, 2751, Australia. maggiemaggie1979@163.com. ^[7] Department of Experimental Research Center, Xiyuan Hospital of China Academy of Chinese Medical Sciences, 1 Xiyuan Caochang, Hai Dian District, Beijing, 100091, China. ljxunljxun@163.com. ^[8] Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA. wangbwangb@126.com. ^[9]

主题词 AMP活化蛋白激酶类(AMP-Activated Protein Kinases);动物(Animals);自噬(Autophagy);小檗碱(Berberine);细胞系(Cell Line);趋化因子CCL3(Chemokine CCL3);趋化因子CCL5(Chemokine CCL5);剂量效应关系, 药物(Dose-Response Relationship, Drug);免疫印迹法(Immunoblotting);炎症介导素类(Inflammation Mediators);白细胞介素10(Interleukin-10);脂蛋白类, LDL(Lipoproteins, LDL);巨噬细胞(Macrophages);小鼠(Mice);信号传导(Signal Transduction);TOR丝氨酸-苏氨酸激酶(TOR Serine-Threonine Kinases);时间因素(Time Factors);增量调节(Up-Regulation)

DOI 10.1186/s12967-015-0450-z

PMID 25884210

发布时间 2022-03-31

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Journal of translational medicine

2015年13卷

92页

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Berberine alleviates ox-LDL induced inflammatory factors by up-regulation of autophagy via AMPK/mTOR signaling pathway.

Journal of translational medicine

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Journal of translational medicine

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Berberine alleviates ox-LDL induced inflammatory factors by up-regulation of autophagy via AMPK/mTOR signaling pathway.

Journal of translational medicine

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Journal of translational medicine

相关期刊

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