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Immuno-magnetoliposomes targeting activated platelets as a potentially human-compatible MRI contrast agent for targeting atherothrombosis.

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第一作者： S,Meier

第一单位： Department of Cardiology and Angiology I, University Heart Center Freiburg, Germany.

作者： S,Meier ^[1] ; G,Pütz ^[2] ; U,Massing ^[3] ; C E,Hagemeyer ^[4] ; D,von Elverfeldt ^[5] ; M,Meissner ^[5] ; K,Ardipradja ^[6] ; S,Barnert ^[7] ; K,Peter ^[8] ; C,Bode ^[1] ; R,Schubert ^[7] ; C,von zur Muhlen ^[9]

作者单位： Department of Cardiology and Angiology I, University Heart Center Freiburg, Germany. ^[1] Department of Clinical Chemistry, University Hospital Freiburg, Germany. ^[2] Department of Clinical Research, Tumor Biology Center Freiburg, Germany; Andreas Hettich GmbH & Co KG, Tuttlingen, Gemany. ^[3] Vascular Biotechnology Laboratory, Baker IDI, Melbourne, Australia. ^[4] Department of Diagnostic Radiology Medical Physics, University Hospital Freiburg, Germany. ^[5] Vascular Biotechnology Laboratory, Baker IDI, Melbourne, Australia; Atherothrombosis and Vascular Laboratory, Baker IDI, Melbourne, Australia. ^[6] Department of Pharmaceutical Technology and Biopharmacy, University of Freiburg, Germany. ^[7] Atherothrombosis and Vascular Laboratory, Baker IDI, Melbourne, Australia. ^[8] Department of Cardiology and Angiology I, University Heart Center Freiburg, Germany. Electronic address: constantin.vonzurmuehlen@universitaets-herzzentrum.de. ^[9]

关键词 Atherosclerosis Liposomes MRI Magnetoliposomes Platelets SPIO

医学主题词血小板(Blood Platelets);造影剂(Contrast Media);人类(Humans);脂质体(Liposomes);磁共振成像(Magnetic Resonance Imaging);磁力学(Magnetics);血栓形成(Thrombosis)

DOI 10.1016/j.biomaterials.2015.02.088

PMID 25890714

发布时间 2015-04-20

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