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Romidepsin in peripheral and cutaneous T-cell lymphoma: mechanistic implications from clinical and correlative data.

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第一作者： Susan E,Bates

第一单位： Developmental Therapeutics Branch, NCI, NIH, Bethesda, MD, USA.

作者： Susan E,Bates ^[1] ; Robin,Eisch ^[1] ; Alexander,Ling ^[2] ; Douglas,Rosing ^[3] ; Maria,Turner ^[4] ; Stefania,Pittaluga ^[5] ; H Miles,Prince ^[6] ; Mark H,Kirschbaum ^[7] ; Steven L,Allen ^[8] ; Jasmine,Zain ^[9] ; Larisa J,Geskin ^[10] ; David,Joske ^[11] ; Leslie,Popplewell ^[12] ; Edward W,Cowen ^[4] ; Elaine S,Jaffe ^[5] ; Jean,Nichols ^[13] ; Sally,Kennedy ^[14] ; Seth M,Steinberg ^[15] ; David J,Liewehr ^[15] ; Louise C,Showe ^[16] ; Caryn,Steakley ^[17] ; John,Wright ^[18] ; Tito,Fojo ^[17] ; Thomas,Litman ^[19] ; Richard L,Piekarz ^[18]

作者单位： Developmental Therapeutics Branch, NCI, NIH, Bethesda, MD, USA. ^[1] Department of Radiology, Warren G Magnuson Clinical Center, NIH, Bethesda, MD, USA. ^[2] Consultative Cardiology, NHLBI, NIH, Bethesda, MD, USA. ^[3] Dermatology Branch, NCI, Bethesda, MD, USA. ^[4] Laboratory of Pathology, CCR, NCI, Bethesda, MD, USA. ^[5] Peter MacCallum Cancer Centre, East Melbourne, Vic., Australia. ^[6] Hematological Malignancies, Penn State Hershey Medical Center, Hershey, PA, USA. ^[7] Hofstra North Shore-LIJ School of Medicine and Monter Cancer Center, Lake Success, NY, USA. ^[8] Columbia University, New York, NY, USA. ^[9] Department of Dermatology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA. ^[10] Sir Charles Gairdner Hospital, Nedlands, WA, Australia. ^[11] City of Hope National Cancer Center, Duarte, CA, USA. ^[12] Celgene Corporation, Cambridge, MA, USA. ^[13] Independent Pharmaceutical Consultant, Boston, MA, USA. ^[14] Biostatistics and Data Management, NCI, Bethesda, MD, USA. ^[15] The Wistar Institute, Philadelphia, PA, USA. ^[16] Center for Cancer Research, NCI, Bethesda, MD, USA. ^[17] Cancer Therapy Evaluation Program, DCTDC, NCI, Bethesda, MD, USA. ^[18] LEO Pharma A/S, Ballerup, Denmark. ^[19]

关键词 T-cell lymphoma chromatin epigenetic therapy histone deacetylase inhibitor romidepsin