Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo.

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作者： Fadi J,Najm ^[1] ; Mayur,Madhavan ^[1] ; Anita,Zaremba ^[2] ; Elizabeth,Shick ^[1] ; Robert T,Karl ^[1] ; Daniel C,Factor ^[1] ; Tyler E,Miller ^[3] ; Zachary S,Nevin ^[1] ; Christopher,Kantor ^[2] ; Alex,Sargent ^[2] ; Kevin L,Quick ^[4] ; Daniela M,Schlatzer ^[5] ; Hong,Tang ^[6] ; Ruben,Papoian ^[6] ; Kyle R,Brimacombe ^[7] ; Min,Shen ^[7] ; Matthew B,Boxer ^[7] ; Ajit,Jadhav ^[7] ; Andrew P,Robinson ^[8] ; Joseph R,Podojil ^[8] ; Stephen D,Miller ^[8] ; Robert H,Miller ^[2] ; Paul J,Tesar ^[9]

作者单位： Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA. ^[1] Department of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA. ^[2] 1] Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA [2] Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA [3] Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA. ^[3] PerkinElmer, 940 Winter Street, Waltham, Massachusetts 02451, USA. ^[4] Center for Proteomics and Bioinformatics, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA. ^[5] Drug Discovery Center, University of Cincinnati College of Medicine, Cincinnati, Ohio 45237, USA. ^[6] National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, Maryland 20850, USA. ^[7] Department of Microbiology-Immunology and Interdepartmental Immunobiology Center, Feinberg School of Medicine, Northwestern University, 303 E. Chicago Avenue, Chicago, Illinois 60611, USA. ^[8] 1] Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA [2] Department of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA. ^[9]