Evaluation of functional characteristics of preactivated thiolated chitosan as potential therapeutic agent for dry mouth syndrome.

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作者： Flavia,Laffleur ^[1] ; Alexander,Fischer ^[1] ; Matthias,Schmutzler ^[2] ; Fabian,Hintzen ^[1] ; Andreas,Bernkop-Schnürch ^[3]

作者单位： Department of Pharmaceutical Technology, Institute of Pharmacy, Center for Molecular Biosciences Innsbruck, University of Innsbruck, Austria. ^[1] Institute of Analytical Chemistry & Radiochemistry, CCB - Center for Chemistry and Biomedicine, University of Innsbruck, Austria. ^[2] Department of Pharmaceutical Technology, Institute of Pharmacy, Center for Molecular Biosciences Innsbruck, University of Innsbruck, Austria. Electronic address: andreas.bernkop@uibk.ac.at. ^[3]

关键词 Chitosan–thioglycolic acid Dry mouth syndrome Mercaptonicotinamide Preactivated thiomers Thiomers

主题词细胞系, 肿瘤(Cell Line, Tumor);壳聚糖(Chitosan);人类(Humans);材料试验(Materials Testing);巯基化合物(Sulfhydryl Compounds);口腔干燥(Xerostomia)

DOI 10.1016/j.actbio.2015.04.016

PMID 25900442

发布时间 2015-05-26

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