Undetected toxicity risk in pharmacogenetic testing for dihydropyrimidine dehydrogenase.

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作者： Felicia Stefania,Falvella ^[1] ; Marta,Caporale ^[2] ; Stefania,Cheli ^[3] ; Antonia,Martinetti ^[4] ; Rosa,Berenato ^[5] ; Claudia,Maggi ^[6] ; Monica,Niger ^[7] ; Francesca,Ricchini ^[8] ; Ilaria,Bossi ^[9] ; Maria,Di Bartolomeo ^[10] ; Elisa,Sottotetti ^[11] ; Francesca Futura,Bernardi ^[12] ; Filippo,de Braud ^[13] ; Emilio,Clementi ^[14] ; Filippo,Pietrantonio ^[15]

作者单位： Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences, University Hospital "Luigi Sacco", Università di Milano, Milan 20157, Italy. falvella.stefania@hsacco.it. ^[1] Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian, Milan 20133, Italy. marta.caporale@istitutotumori.mi.it. ^[2] Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences, University Hospital "Luigi Sacco", Università di Milano, Milan 20157, Italy. cheli.stefania@hsacco.it. ^[3] Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian, Milan 20133, Italy. antonia.martinetti@istitutotumori.mi.it. ^[4] Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian, Milan 20133, Italy. rosa.berenato@istitutotumori.mi.it. ^[5] Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian, Milan 20133, Italy. claudia.maggi@istitutotumori.mi.it. ^[6] Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian, Milan 20133, Italy. monica.niger@istitutotumori.mi.it. ^[7] Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian, Milan 20133, Italy. francesca.ricchini@istitutotumori.mi.it. ^[8] Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian, Milan 20133, Italy. ilaria.bossi@istitutotumori.mi.it. ^[9] Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian, Milan 20133, Italy. maria.dibartolomeo@istitutotumori.mi.it. ^[10] Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian, Milan 20133, Italy. elisa.sottotetti@istitutotumori.mi.it. ^[11] Department of Experimental Medicine, Section of Pharmacology "L. Donatelli", Faculty of Medicine and Surgery, Second University of Naples, Naples 80138, Italy. bernardi.francesca.futura@gmail.com. ^[12] Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian, Milan 20133, Italy. filippo.debraud@istitutotumori.mi.it. ^[13] Scientific Institute, IRCCS E. Medea, Bosisio Parini, Lecco 23842, Italy. emilio.clementi@unimi.it. ^[14] Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences, Consiglio Nazionale delle Ricerche Institute of Neuroscience, University Hospital "Luigi Sacco", Università di Milano, Milan 20157, Italy. emilio.clementi@unimi.it. ^[15] Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian, Milan 20133, Italy. filippo.pietrantonio@istitutotumori.mi.it. ^[16]