The structure of the PanD/PanZ protein complex reveals negative feedback regulation of pantothenate biosynthesis by coenzyme A.

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作者： Diana C F,Monteiro ^[1] ; Vijay,Patel ^[2] ; Christopher P,Bartlett ^[2] ; Shingo,Nozaki ^[3] ; Thomas D,Grant ^[4] ; James A,Gowdy ^[1] ; Gary S,Thompson ^[2] ; Arnout P,Kalverda ^[2] ; Edward H,Snell ^[4] ; Hironori,Niki ^[5] ; Arwen R,Pearson ^[6] ; Michael E,Webb ^[7]

作者单位： Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK; School of Chemistry, University of Leeds, Leeds LS2 9JT, UK; Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK. ^[1] Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK; Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK. ^[2] Microbial Genetics Laboratory, Genetic Strains Research Center, National Institute of Genetics, 1111 Yata, Mishima, Shizuoka 411-8540, Japan. ^[3] Hauptmann-Woodward Medical Research Institute, Buffalo, NY 14203, USA. ^[4] Microbial Genetics Laboratory, Genetic Strains Research Center, National Institute of Genetics, 1111 Yata, Mishima, Shizuoka 411-8540, Japan; Department of Genetics, Graduate University for Advanced Studies (Sokendai), 1111 Yata, Mishima, Shizuoka 411-8540, Japan. ^[5] Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK; Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK. Electronic address: arwen.pearson@cfel.de. ^[6] Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK; School of Chemistry, University of Leeds, Leeds LS2 9JT, UK. Electronic address: m.e.webb@leeds.ac.uk. ^[7]