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Altered Phenotype of β-Cells and Other Pancreatic Cell Lineages in Patients With Diffuse Congenital Hyperinsulinism in Infancy Caused by Mutations in the ATP-Sensitive K-Channel.

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第一作者: Rachel J,Salisbury
第一单位: Centre for Endocrinology and Diabetes, Institute of Human Development, Faculty of Medical and Human Sciences, Manchester Academic Health Sciences Centre, The University of Manchester, Manchester, U.K.
作者单位: Centre for Endocrinology and Diabetes, Institute of Human Development, Faculty of Medical and Human Sciences, Manchester Academic Health Sciences Centre, The University of Manchester, Manchester, U.K. [1] Faculty of Life Sciences, The University of Manchester, Manchester, U.K. [2] Centre for Endocrinology and Diabetes, Institute of Human Development, Faculty of Medical and Human Sciences, Manchester Academic Health Sciences Centre, The University of Manchester, Manchester, U.K. Department of Endocrinology, Central Manchester University Hospitals NHS Foundation Trust, Manchester, U.K. [3] Faculty of Life Sciences, The University of Manchester, Manchester, U.K. Department of Paediatric Endocrinology, Central Manchester University Hospitals NHS Foundation Trust, Manchester, U.K. [4] Erasmus MC, Rotterdam, the Netherlands Department of Pathology, Reinier de Graaf Hospital, Delft, the Netherlands. [5] Diabetes Research & Wellness Foundation Human Islet Isolation Facility, Nuffield Department of Surgical Sciences and Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, U.K. [6] Department of Paediatric Histopathology, Central Manchester University Hospitals NHS Foundation Trust, Manchester, U.K. [7] Centre for Endocrinology and Diabetes, Institute of Human Development, Faculty of Medical and Human Sciences, Manchester Academic Health Sciences Centre, The University of Manchester, Manchester, U.K. Department of Paediatric Endocrinology, Central Manchester University Hospitals NHS Foundation Trust, Manchester, U.K. [8] Faculty of Life Sciences, The University of Manchester, Manchester, U.K. neil.hanley@manchester.ac.uk mark.dunne@manchester.ac.uk. [9] Centre for Endocrinology and Diabetes, Institute of Human Development, Faculty of Medical and Human Sciences, Manchester Academic Health Sciences Centre, The University of Manchester, Manchester, U.K. Department of Endocrinology, Central Manchester University Hospitals NHS Foundation Trust, Manchester, U.K. neil.hanley@manchester.ac.uk mark.dunne@manchester.ac.uk. [10]
DOI 10.2337/db14-1202
PMID 25931474
发布时间 2025-05-29
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