Hydroxymethylcytosine and demethylation of the γ-globin gene promoter during erythroid differentiation.
第一作者:
Maria Armila,Ruiz
第一单位:
a Jesse Brown VA Medical Center ; Chicago , IL , USA.
作者:
关键词
5hmC, 5-hydroxymethylcytosine; 5mC, 5-methylcytosine; HbF, fetal hemoglobin; DNMT, DNA methyltransferase; BM, bone marrow; FL, fetal liver; LSD1, lysine specific demethylase 1; TC, tranylcypromineDNA methylationbaboondecitabineerythropoiesisglobin gene switchinghydroxymethylcytosinetranylcyprominevitamin Cγ-globin gene
主题词
5-甲基胞嘧啶(5-Methylcytosine);动物(Animals);动物, 新生(Animals, Newborn);抗肿瘤药(Antineoplastic Agents);抗坏血酸(Ascorbic Acid);阿扎胞苷(Azacitidine);骨髓细胞(Bone Marrow Cells);细胞分化(Cell Differentiation);细胞, 培养的(Cells, Cultured);胞嘧啶(Cytosine);DNA甲基化(DNA Methylation);双加氧酶类(Dioxygenases);红系细胞(Erythroid Cells);组蛋白脱甲基酶类(Histone Demethylases);人类(Humans);羟基脲(Hydroxyurea);肝(Liver);猎神狒狒(Papio anubis);启动区, 遗传(Promoter Regions, Genetic);反苯环丙铵(Tranylcypromine);γ珠蛋白类(gamma-Globins)
DOI
10.1080/15592294.2015.1039220
PMID
25932923
发布时间
2018-12-02
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Epigenetics
397-407页
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