换一批Pharmacological characterization of the newly synthesized 5-amino-N-butyl-2-(4-ethoxyphenoxy)-benzamide hydrochloride (BED) as a potent NCX3 inhibitor that worsens anoxic injury in cortical neurons, organotypic hippocampal cultures, and ischemic brain.
第一作者：
Agnese,Secondo
第一单位：
†Department of Neuroscience, Reproductive and Odontostomatological Sciences, School of Medicine, "Federico II" University of Naples, Via Pansini 5, 80131 Naples, Italy.
作者：
医学主题词
动物(Animals);苯甲酰胺类(Benzamides);脑(Brain);脑缺血(Brain Ischemia);钙(Calcium);细胞死亡(Cell Death);细胞低氧(Cell Hypoxia);细胞系(Cell Line);中枢神经系统药物(Central Nervous System Agents);仓鼠亚科(Cricetinae);疾病模型, 动物(Disease Models, Animal);狗(Dogs);剂量效应关系, 药物(Dose-Response Relationship, Drug);药物评价, 临床前(Drug Evaluation, Preclinical);葡萄糖(Glucose);梗死, 大脑中动脉(Infarction, Middle Cerebral Artery);小鼠, 近交C57BL(Mice, Inbred C57BL);突变(Mutation);神经元(Neurons);蛋白质亚型(Protein Isoforms);大鼠(Rats);钠钙交换蛋白(Sodium-Calcium Exchanger);组织培养技术(Tissue Culture Techniques)
DOI
10.1021/acschemneuro.5b00043
PMID
25942323
发布时间
2015-08-19
- 浏览10
ACS chemical neuroscience
1361-70页
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文
