Anti-tumor activity of selective inhibitors of XPO1/CRM1-mediated nuclear export in diffuse malignant peritoneal mesothelioma: the role of survivin.
第一作者:
Michelandrea,De Cesare
第一单位:
Molecular Pharmacology Unit, Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.
作者:
主题词
丙烯酰胺类(Acrylamides);主动转运, 细胞核(Active Transport, Cell Nucleus);动物(Animals);抗肿瘤药(Antineoplastic Agents);细胞凋亡(Apoptosis);细胞系, 肿瘤(Cell Line, Tumor);周期素依赖激酶抑制剂p21(Cyclin-Dependent Kinase Inhibitor p21);剂量效应关系, 药物(Dose-Response Relationship, Drug);酶联免疫吸附测定(Enzyme-Linked Immunosorbent Assay);人类(Humans);肼类(Hydrazines);凋亡抑制蛋白质类(Inhibitor of Apoptosis Proteins);核胞浆转运蛋白类(Karyopherins);肺肿瘤(Lung Neoplasms);间皮瘤(Mesothelioma);小鼠(Mice);小鼠, SCID(Mice, SCID);肿瘤蛋白质类(Neoplasm Proteins);恶二唑类(Oxadiazoles);腹膜肿瘤(Peritoneal Neoplasms);受体, 胞质和核(Receptors, Cytoplasmic and Nuclear);噻唑类(Thiazoles);三唑类(Triazoles);肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53)
DOI
10.18632/oncotarget.3761
PMID
25948791
发布时间
2023-12-13
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Oncotarget
13119-32页
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