<i>Dab2</i>, a negative regulator of DC immunogenicity, is an attractive molecular target for DC-based immunotherapy.
第一作者:
Md Selim,Ahmed
第一单位:
Department of Biological Science; Sungkyunkwan University ; Suwon, Gyounggi-do, Republic of Korea.
作者:
关键词
BAT, blocking the TGF-β-activated translation elementBM, bone marrowCFSE, 5, 6-carboxyfluorescein succinimidyl esterCTL, cytotoxic T lymphocyteDCs, dendritic cellsDab2Dab2, disabled-2 adaptor proteinDab2KD, Dab2-knockdownFoxp3, forkhead box P3GM-CSF, granulocyte-macrophage colony stimulating factorOT-1 and OT-2 mice, OVA257–264 and OVA323–339-peptide-specific T cell receptor transgenic miceOVA, ovalbuminPI3K, phosphoinositide-3 kinaseSTAT5, transducer and activator of transcription 5TGF-β, transforming growth factor-βTreg, regulatory TWT, wild typedendritic cellshMoDC, human monocyte-derived dendritic cellhnRNP E1, heterogeneous nuclear ribonucleoprotein E1imDC, immature DCimmunogenicitymDC, mature DCmolecular target
DOI
10.4161/2162402X.2014.984550
PMID
25949867
发布时间
2021-01-12
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Oncoimmunology
e984550页
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