CD8<sup>+</sup>/FOXP3<sup>+</sup>-ratio in osteosarcoma microenvironment separates survivors from non-survivors: a multicenter validated retrospective study.
第一作者:
Benedikt,Fritzsching
第一单位:
Department of Translational Pulmonology; Translational Lung Research Center (TLRC); Member of the German Center for Lung; University of Heidelberg , Heidelberg, Germany ; Divison of Pediatric Pulmonology & Allergy and Cystic Fibrosis Center; Department of Pediatric Oncology, Hematology; Immunology and Pulmonology; University of Heidelberg , Heidelberg, Germany.
作者:
关键词
CD8+ T cellsCD8/FOXP3-ratioCONSORT, consolidated standard of reporting trialsCOSS, Cooperative German–Austrian–Swiss Osteosarcoma Study GroupEORTC, the European Organization for Research and Treatment of CancerFFPE, formalin-fixed and paraffin embeddedIDO, Indoleamine 2, 3-dioxygenaseMAP, methotrexate-cisplatin-doxorubicinPD-L1, Programmed-death-Ligand-1REMARK, reporting recommendations for tumor marker prognostic studiesTIL, tumor infiltrating lymphocyteTNFα, tumornecrosis factor-αTNM-I, tumor, nodes, metastases-immunoTreg, regulatory Tcell.immunoscoreosteosarcomaregulatory T cellstumor microenvironment
DOI
10.4161/2162402X.2014.990800
PMID
25949908
发布时间
2022-03-17
- 浏览54
Oncoimmunology
e990800页
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