Oncocin Onc72 is efficacious against antibiotic-susceptible Klebsiella pneumoniae ATCC 43816 in a murine thigh infection model.

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作者： Daniel,Knappe ^[1] ; Knut,Adermann ^[2] ; Ralf,Hoffmann ^[3]

作者单位： Institute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, Universität Leipzig, Leipzig, Germany. ^[1] Center for Biotechnology and Biomedicine, Universität Leipzig, Leipzig, Germany. ^[2] AMP-Therapeutics GmbH, Leipzig, Germany. ^[3]

关键词 Klebsiella pneumonia antimicrobial peptide meropenem oncocin proline-rich thigh infection

主题词动物(Animals);抗微生物阳离子肽类(Antimicrobial Cationic Peptides);细菌感染(Bacterial Infections);疾病模型, 动物(Disease Models, Animal);肺炎克雷伯菌(Klebsiella pneumoniae);小鼠(Mice);肌, 骨骼(Muscle, Skeletal)

DOI 10.1002/bip.22668

PMID 25968331

发布时间 2016-12-30

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