换一批Sequencing of 279 cancer genes in ampullary carcinoma reveals trends relating to histologic subtypes and frequent amplification and overexpression of ERBB2 (HER2).
第一作者：
Jaclyn F,Hechtman
第一单位：
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
作者：
医学主题词
成年人(Adult);老年人(Aged);老年人, 80以上(Aged, 80 and over);肝胰管壶腹(Ampulla of Vater);癌(Carcinoma);胆总管肿瘤(Common Bile Duct Neoplasms);周期素依赖激酶抑制剂p16(Cyclin-Dependent Kinase Inhibitor p16);DNA突变分析(DNA Mutational Analysis);女(雌)性(Female);GTP磷酸水解酶类(GTP Phosphohydrolases);基因扩增(Gene Amplification);基因缺失(Gene Deletion);基因表达谱(Gene Expression Profiling);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);疾病遗传易感性(Genetic Predisposition to Disease);人类(Humans);免疫组织化学(Immunohistochemistry);原位杂交(In Situ Hybridization);男(雄)性(Male);膜蛋白质类(Membrane Proteins);中年人(Middle Aged);突变(Mutation);寡核苷酸序列分析(Oligonucleotide Array Sequence Analysis);表型(Phenotype);试验预期值(Predictive Value of Tests);原癌基因蛋白质类p21(ras)(Proto-Oncogene Proteins p21(ras));肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53);增量调节(Up-Regulation)
DOI
10.1038/modpathol.2015.57
PMID
25975284
发布时间
2023-02-10
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Modern pathology
1123-9页
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