换一批Development of a candidate influenza vaccine based on virus-like particles displaying influenza M2e peptide into the immunodominant region of hepatitis B core antigen: Broad protective efficacy of particles carrying four copies of M2e.
第一作者：
Liudmila M,Tsybalova
第一单位：
Research Institute of Influenza, Russian Federation Ministry of Health, St. Petersburg, Russia. Electronic address: sovet@influenza.spb.ru.
作者：
主题词
动物(Animals);抗体, 病毒(Antibodies, Viral);血液(Blood);支气管肺泡灌洗液(Bronchoalveolar Lavage Fluid);交叉保护(Cross Protection);交叉反应(Cross Reactions);疾病模型, 动物(Disease Models, Animal);表位(Epitopes);大肠杆菌(Escherichia coli);女(雌)性(Female);基因表达(Gene Expression);乙型肝炎核心抗原(Hepatitis B Core Antigens);免疫球蛋白G(Immunoglobulin G);流感疫苗(Influenza Vaccines);肺(Lung);小鼠, 近交BALB C(Mice, Inbred BALB C);诱变, 插入(Mutagenesis, Insertional);正黏病毒科感染(Orthomyxoviridae Infections);重组融合蛋白质类(Recombinant Fusion Proteins);存活率分析(Survival Analysis);T淋巴细胞(T-Lymphocytes);疫苗, 合成(Vaccines, Synthetic);疫苗, 病毒样颗粒(Vaccines, Virus-Like Particle);病毒载量(Viral Load);病毒基质蛋白质类(Viral Matrix Proteins)
DOI
10.1016/j.vaccine.2015.04.073
PMID
25976545
发布时间
2015-06-15
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Vaccine
3398-406页
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