Optimal programs of pathway control: dissecting the influence of pathway topology and feedback inhibition on pathway regulation.

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作者： Gundián M,de Hijas-Liste ^[1] ; Eva,Balsa-Canto ^[2] ; Jan,Ewald ^[3] ; Martin,Bartl ^[4] ; Pu,Li ^[5] ; Julio R,Banga ^[6] ; Christoph,Kaleta ^[7]

作者单位： Bioprocess Engineering Group, Spanish National Research Council, IIM-CSIC, C/Eduardo Cabello 6, Vigo, 36208, Spain. gundian@iim.csic.es. ^[1] Bioprocess Engineering Group, Spanish National Research Council, IIM-CSIC, C/Eduardo Cabello 6, Vigo, 36208, Spain. ebalsa@iim.csic.es. ^[2] esearch Group Theoretical Systems Biology, Friedrich Schiller University Jena, Leutragraben 1,, Jena, 07743, Germany. jan.ewald@uni-jena.de. ^[3] esearch Group Theoretical Systems Biology, Friedrich Schiller University Jena, Leutragraben 1,, Jena, 07743, Germany. ebalsa@iim.csic.es. ^[4] Simulation and Optimal Processes Group, Ilmenau University of Technology, P.O.Box 100565, Ilmenau, 98684, Germany. ebalsa@iim.csic.es. ^[5] Bioprocess Engineering Group, Spanish National Research Council, IIM-CSIC, C/Eduardo Cabello 6, Vigo, 36208, Spain. julio@iim.csic.es. ^[6] esearch Group Theoretical Systems Biology, Friedrich Schiller University Jena, Leutragraben 1,, Jena, 07743, Germany. c.kaleta@iem.uni-kiel.de. ^[7] Research Group Medical Systems Biology, Christian-Albrechts-University Kiel, Brunswiker Straße 10, Kiel, 24105, Germany. c.kaleta@iem.uni-kiel.de. ^[8]

主题词算法(Algorithms);别构调节(Allosteric Regulation);计算生物学(Computational Biology);大肠杆菌(Escherichia coli);反馈, 生理(Feedback, Physiological);基因表达调控, 细菌(Gene Expression Regulation, Bacterial);代谢网络和途径(Metabolic Networks and Pathways);模型, 理论(Models, Theoretical);蛋白质类(Proteins);蛋白质组学(Proteomics)

DOI 10.1186/s12859-015-0587-z

PMID 25982966

发布时间 2018-12-02

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BMC bioinformatics

2015年16卷

163页

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Optimal programs of pathway control: dissecting the influence of pathway topology and feedback inhibition on pathway regulation.

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Optimal programs of pathway control: dissecting the influence of pathway topology and feedback inhibition on pathway regulation.

BMC bioinformatics

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