Co-delivery of hydrophobic paclitaxel and hydrophilic AURKA specific siRNA by redox-sensitive micelles for effective treatment of breast cancer.
作者:
主题词
动物(Animals);抗肿瘤药, 植物(Antineoplastic Agents, Phytogenic);乳腺肿瘤(Breast Neoplasms);细胞系, 肿瘤(Cell Line, Tumor);细胞存活(Cell Survival);迟效制剂(Delayed-Action Preparations);扩散(Diffusion);复方合剂(Drug Combinations);人类(Humans);亲水和疏水相互作用(Hydrophobic and Hydrophilic Interactions);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);微胶粒(Micelles);纳米囊(Nanocapsules);纳米共轭体(Nanoconjugates);氧化还原(Oxidation-Reduction);紫杉酚(Paclitaxel);RNA, 小分子干扰(RNA, Small Interfering);治疗结果(Treatment Outcome)
DOI
10.1016/j.biomaterials.2015.05.022
PMID
25996409
发布时间
2022-06-09
- 浏览53
Biomaterials
10-25页
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