RIPK1 regulates survival of human melanoma cells upon endoplasmic reticulum stress through autophagy.
作者:
关键词
3-MA, 3-methyladenineAMPK, AMP-activated protein kinaseATF6, activating transcription factor 6Baf A1, bafilomycin A1CAMKK2, calcium/calmodulin-dependent protein kinase kinase 2: βEIF2AK3/PERK, eukaryotic translation initiation factor 2-α kinase 3ER, endoplasmic reticulumERN1/IRE1, endoplasmic reticulum to nucleus signaling 1HSF1, heat shock transcription factor 1HSPA5, heat shock 70kDa protein 5 (glucose-regulated protein: 78kDa)MAP2K1/MEK1, mitogen-activated protein kinase kinase 1MAPK, mitogen-activated protein kinaseMAPK1/ERK2, mitogen-activated protein kinase 1MAPK11/p38β, mitogen-activated protein kinase 11MAPK12/p38γ, mitogen-activated protein kinase 12MAPK13/p38δ, mitogen-activated protein kinase 13MAPK14/p38α, mitogen-activated protein kinase 14MAPK3/ERK1, mitogen-activated protein kinase 3MAPK8/JNK1, mitogen-activated protein kinase 8MAPK9/JNK2, mitogen-activated protein kinase 9NFKB1, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1PRKAA1, protein kinase AMP-activated: α 1 catalytic subunitRIPK1RIPK1, receptor (TNFRSF)-interacting protein kinase 1SQSTM1/p62, sequestosome 1TG, thapsigarginTM, tunicamycinTNFRSF1A/TNFR1, tumor necrosis factor receptor superfamily: member 1AUPR, unfolded protein responseXBP1, x-box binding protein 1autophagycell deathendoplasmic reticulum stressmelanoma
主题词
细胞凋亡(Apoptosis);凋亡调节蛋白质类(Apoptosis Regulatory Proteins);自噬(Autophagy);细胞系, 肿瘤(Cell Line, Tumor);细胞存活(Cell Survival);细胞保护(Cytoprotection);DNA结合蛋白质类(DNA-Binding Proteins);酶激活(Enzyme Activation);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);黑色素瘤(Melanoma);膜蛋白质类(Membrane Proteins);丝裂原活化蛋白激酶8(Mitogen-Activated Protein Kinase 8);丝裂原活化蛋白激酶9(Mitogen-Activated Protein Kinase 9);模型, 生物学(Models, Biological);磷酰化(Phosphorylation);原癌基因蛋白质类(Proto-Oncogene Proteins);受体作用蛋白丝氨酸苏氨酸激酶类(Receptor-Interacting Protein Serine-Threonine Kinases);毒胡萝卜内酯(Thapsigargin);转录因子(Transcription Factors);衣霉素(Tunicamycin);增量调节(Up-Regulation)
DOI
10.1080/15548627.2015.1049800
PMID
26018731
发布时间
2024-05-20
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Autophagy
975-94页
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