首页> Cellular signalling> The BARD1 BRCT domain contributes to p53 binding, cytoplasmic and mitochondrial localization, and apoptotic function.

The BARD1 BRCT domain contributes to p53 binding, cytoplasmic and mitochondrial localization, and apoptotic function.

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第一作者： Varsha,Tembe

第一单位： Centre for Cancer Research, The Westmead Millennium Institute for Medical Research, The University of Sydney, Westmead, NSW 2145, Australia.

作者： Varsha,Tembe ^[1] ; Estefania,Martino-Echarri ^[1] ; Kamila A,Marzec ^[1] ; Myth T S,Mok ^[1] ; Kirsty M,Brodie ^[1] ; Kate,Mills ^[1] ; Ying,Lei ^[1] ; Anna,DeFazio ^[1] ; Helen,Rizos ^[1] ; Emma,Kettle ^[2] ; Ross,Boadle ^[2] ; Beric R,Henderson ^[3]

作者单位： Centre for Cancer Research, The Westmead Millennium Institute for Medical Research, The University of Sydney, Westmead, NSW 2145, Australia. ^[1] Electron Microscopy Unit, Institute for Clinical Pathology and Medical Research, Westmead Hospital, Westmead, NSW 2145, Australia. ^[2] Centre for Cancer Research, The Westmead Millennium Institute for Medical Research, The University of Sydney, Westmead, NSW 2145, Australia. Electronic address: beric.henderson@sydney.edu.au. ^[3]

关键词 Apoptosis BARD1 BCL-2 Mitochondria p53