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首页> The Journal of biological chemistry> Complex Formation between Two Biosynthetic Enzymes Modifies the Allosteric Regulatory Properties of Both: AN EXAMPLE OF MOLECULAR SYMBIOSIS.

Complex Formation between Two Biosynthetic Enzymes Modifies the Allosteric Regulatory Properties of Both: AN EXAMPLE OF MOLECULAR SYMBIOSIS.

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作者： Nicola J,Blackmore ^[1] ; Ali Reza,Nazmi ^[1] ; Richard D,Hutton ^[1] ; Melissa N,Webby ^[1] ; Edward N,Baker ^[2] ; Geoffrey B,Jameson ^[3] ; Emily J,Parker ^[4]

作者单位： Maurice Wilkins Centre and Biomolecular Interaction Centre, Department of Chemistry, University of Canterbury, Christchurch 8140, New Zealand. ^[1] Maurice Wilkins Centre and School of Biological Sciences, University of Auckland, Auckland 1142, New Zealand. ^[2] Institute of Fundamental Sciences, Massey University, Palmerston North 4442, New Zealand. Electronic address: G.B.Jameson@massey.ac.nz. ^[3] Maurice Wilkins Centre and Biomolecular Interaction Centre, Department of Chemistry, University of Canterbury, Christchurch 8140, New Zealand. Electronic address: emily.parker@canterbury.ac.nz. ^[4]

关键词 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase Mycobacterium tuberculosis TB allosteric regulation chorismate mutase enzyme catalysis oligomer protein complex protein-protein interaction shikimate

主题词 3-脱氧-7-磷酸庚糖酸合酶(3-Deoxy-7-Phosphoheptulonate Synthase);别构调节(Allosteric Regulation);氨基酸类, 芳香(Amino Acids, Aromatic);分支酸盐变位酶(Chorismate Mutase);结晶学, X线(Crystallography, X-Ray);人类(Humans);结核分枝杆菌(Mycobacterium tuberculosis);蛋白质多聚化(Protein Multimerization);结核(Tuberculosis)

DOI 10.1074/jbc.M115.638700

PMID 26032422

发布时间 2021-03-16

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The Journal of biological chemistry

The Journal of biological chemistry

2015年290卷29期

18187-18198页

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