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首页> Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association> Pharmacological inhibition of NADPH oxidase protects against cisplatin induced nephrotoxicity in mice by two step mechanism.

Pharmacological inhibition of NADPH oxidase protects against cisplatin induced nephrotoxicity in mice by two step mechanism.

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作者： Yimin,Wang ^[1] ; Xiao,Luo ^[2] ; Hao,Pan ^[1] ; Wei,Huang ^[3] ; Xueping,Wang ^[1] ; Huali,Wen ^[1] ; Kezhen,Shen ^[4] ; Baiye,Jin ^[5]

作者单位： Department of Urology, The First Affiliated Hospital, College of Medicine, Zhejiang University, #79 Qinchun Road, Hangzhou, Zhejiang 310003, China. ^[1] Department of Urology, The First People's Hospital of Tongxiang City, Tongxiang, Zhejiang Province 314500, China. ^[2] Department of Urology, The People's Hospital of Yueqing City, Yueqing, Zhejiang Province 325600, China. ^[3] Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, Hangzhou, Zhejiang Province 310003, China. ^[4] Department of Urology, The First Affiliated Hospital, College of Medicine, Zhejiang University, #79 Qinchun Road, Hangzhou, Zhejiang 310003, China. Electronic address: jinbaiye1964@aliyun.com. ^[5]

关键词 Kidney failure NOX Oncology Oxidative stress T24 cell line

主题词苯乙酮类(Acetophenones);动物(Animals);抗肿瘤药(Antineoplastic Agents);细胞凋亡(Apoptosis);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);顺铂(Cisplatin);剂量效应关系, 药物(Dose-Response Relationship, Drug);酶抑制剂(Enzyme Inhibitors);肾(Kidney);男(雄)性(Male);小鼠, 近交C57BL(Mice, Inbred C57BL);氧化性应激(Oxidative Stress);胡黄连属(Picrorhiza);植物根(Plant Roots);预防和防护用药(Protective Agents);肾功能不全(Renal Insufficiency)

DOI 10.1016/j.fct.2015.05.007

PMID 26032634

发布时间 2017-11-16

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Food and chemical toxicology

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