Local delivery of FTY720 in PCL membrane improves SCI functional recovery by reducing reactive astrogliosis.

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作者： Junjuan,Wang ^[1] ; Jiaqiu,Wang ^[2] ; Ping,Lu ^[1] ; Youzhi,Cai ^[3] ; Yafei,Wang ^[1] ; Lan,Hong ^[1] ; Hao,Ren ^[1] ; Boon Chin,Heng ^[4] ; Hua,Liu ^[1] ; Jing,Zhou ^[5] ; Hongwei,Ouyang ^[6]

作者单位： Center for Stem Cell and Tissue Engineering, School of Medicine, Zhejiang University, Hangzhou, China; Key Laboratory of Tissue Engineering and Regenerative Medicine of Zhejiang Province, Hangzhou, China. ^[1] Center for Stem Cell and Tissue Engineering, School of Medicine, Zhejiang University, Hangzhou, China; The 2nd Affliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China. ^[2] The 1st Affliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China. ^[3] Department of Biosystems Science & Engineering (D-BSSE), ETH-Zurich, Basel, Switzerland. ^[4] Center for Stem Cell and Tissue Engineering, School of Medicine, Zhejiang University, Hangzhou, China; Key Laboratory of Tissue Engineering and Regenerative Medicine of Zhejiang Province, Hangzhou, China. Electronic address: zhoujing@zju.edu.cn. ^[5] Center for Stem Cell and Tissue Engineering, School of Medicine, Zhejiang University, Hangzhou, China; Key Laboratory of Tissue Engineering and Regenerative Medicine of Zhejiang Province, Hangzhou, China; Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China. ^[6]

关键词 Astrogliosis Drug release FTY720 S1P Spinal cord injury