Characterization of mice harboring a variant of EPCR with impaired ability to bind protein C: novel role of EPCR in hematopoiesis.-论文-万方医学网

作者： Laura,Pepler ^[1] ; Pei,Yu ^[2] ; Dhruva J,Dwivedi ^[3] ; Bernardo L,Trigatti ^[2] ; Patricia C,Liaw ^[3]

作者单位： Department of Medical Sciences, McMaster University, Hamilton, ON, Canada; Thrombosis and Atherosclerosis Research Institute, Hamilton, ON, Canada; and. ^[1] Thrombosis and Atherosclerosis Research Institute, Hamilton, ON, Canada; and Department of Biochemistry and Biomedical Science, and. ^[2] Thrombosis and Atherosclerosis Research Institute, Hamilton, ON, Canada; and Department of Medicine, McMaster University, Hamilton, ON, Canada. ^[3]

主题词氨基酸取代(Amino Acid Substitution);动物(Animals);抗凝血酶Ⅲ(Antithrombin III);骨髓移植(Bone Marrow Transplantation);细胞系(Cell Line);女(雌)性(Female);血细胞生成(Hematopoiesis);炎症(Inflammation);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 突变型(Mice, Mutant Strains);小鼠, 转基因(Mice, Transgenic);诱变, 定点(Mutagenesis, Site-Directed);突变蛋白质类(Mutant Proteins);肽水解酶类(Peptide Hydrolases);蛋白质结合(Protein Binding);蛋白质C(Protein C);蛋白质相互作用域和基序(Protein Interaction Domains and Motifs);受体, 细胞表面(Receptors, Cell Surface);脾大(Splenomegaly);血栓形成(Thrombosis)

DOI 10.1182/blood-2014-02-558940

PMID 26045607

发布时间 2021-02-02

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Characterization of mice harboring a variant of EPCR with impaired ability to bind protein C: novel role of EPCR in hematopoiesis.

Blood

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Characterization of mice harboring a variant of EPCR with impaired ability to bind protein C: novel role of EPCR in hematopoiesis.

Blood

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Blood

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