Genetic variants in 3'-UTRs of methylenetetrahydrofolate reductase (MTHFR) predict colorectal cancer susceptibility in Koreans.

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作者： Young Joo,Jeon ^[1] ; Jong Woo,Kim ^[2] ; Hye Mi,Park ^[1] ; Jung O,Kim ^[1] ; Hyo Geun,Jang ^[1] ; Jisu,Oh ^[3] ; Seong Gyu,Hwang ^[3] ; Sung Won,Kwon ^[2] ; Doyeun,Oh ^[3] ; Nam Keun,Kim ^[1]

作者单位： Institute for Clinical Research, School of Medicine, CHA University, 351 Yatap-dong, Bundang-gu, Seongnam 463-712, South Korea. ^[1] Department of Surgery, School of Medicine, CHA University, 351 Yatap-dong, Bundang-gu, Seongnam 463-712, South Korea. ^[2] Department of Internal Medicine, School of Medicine, CHA University, 351 Yatap-dong, Bundang-gu, Seongnam 463-712, South Korea. ^[3]

主题词 3'非翻译区(3' Untranslated Regions);腺癌(Adenocarcinoma);老年人(Aged);结直肠肿瘤(Colorectal Neoplasms);女(雌)性(Female);叶酸(Folic Acid);基因频率(Gene Frequency);遗传关联研究(Genetic Association Studies);疾病遗传易感性(Genetic Predisposition to Disease);高半胱氨酸(Homocysteine);人类(Humans);男(雄)性(Male);亚甲基四氢叶酸还原酶(NADPH)(Methylenetetrahydrofolate Reductase (NADPH2));中年人(Middle Aged);多态性, 单核苷酸(Polymorphism, Single Nucleotide);韩国(Republic of Korea)

DOI 10.1038/srep11006

PMID 26046315

发布时间 2018-11-13

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Genetic variants in 3'-UTRs of methylenetetrahydrofolate reductase (MTHFR) predict colorectal cancer susceptibility in Koreans.

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Genetic variants in 3'-UTRs of methylenetetrahydrofolate reductase (MTHFR) predict colorectal cancer susceptibility in Koreans.

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