换一批Parkinsonian toxin-induced oxidative stress inhibits basal autophagy in astrocytes via NQO2/quinone oxidoreductase 2: Implications for neuroprotection.
第一作者：
Elzbieta,Janda
第一单位：
a Department of Health Sciences; University "Magna Graecia"; Campus Germaneto ; Catanzaro , Italy.
作者：
关键词
AVs, autophagic vacuolesAb, antibodyBNAH, benzyldihydronicotinamide ribosideCA-DCF-DA, 5(6)-carboxy-2′,7′ dichlorofluorescein diacetateCQ, chloroquineDMEM, Dulbecco's modified Eagle's mediumDMSO, dimethyl sulfoxideFACS, flow cytometryGFAP, glial fibrillary acidic proteinGFP, green fluorescent proteinK3, menadioneMAPK, mitogen-activated protein kinaseMFI, mean fluorescence intensityMPTP, 1-methyl 4-phenyl 1,2,3,6-tetraidro-piridineMitoSOX, 3,8-phenanthridinediamine, 5-(6′-triphenylphosphoniumhexyl)-5,6 dihydro-6-phenylNFE2L2, nuclear factor, erythroid 2-like 2NMDPEF, N-[2-(2-methoxy-6H-dipyrido[2,3-a:3,2-e]pyrrolizin-11-yl)ethyl]-2-furamide]NQO2OS, oxidative stressPBS, phosphate-buffered salinePQ, paraquatROSROS, reactive oxygen speciesRT, room temperatureSN, substantia nigraTTBS, Tween-Tris buffered salineWB, western blottingastrocytesmacroautophagyp-, phosphorylatedparaquatparkinson diseaseshRNA, short harpin ribonucleic acidsiRNA, small interfering ribonucleic acid
医学主题词
乙酰半胱氨酸(Acetylcysteine);衔接蛋白质类, 信号转导(Adaptor Proteins, Signal Transducing);动物(Animals);抗氧化剂(Antioxidants);星形细胞(Astrocytes);星形细胞瘤(Astrocytoma);自噬(Autophagy);二苯甲基化合物(Benzhydryl Compounds);酶抑制剂(Enzyme Inhibitors);甲酰胺类(Formamides);小鼠(Mice);微管相关蛋白质类(Microtubule-Associated Proteins);NF-E2相关因子2(NF-E2-Related Factor 2);神经保护药(Neuroprotective Agents);神经毒素类(Neurotoxins);氧化性应激(Oxidative Stress);百草枯(Paraquat);帕金森病(Parkinson Disease);吞噬体(Phagosomes);醌还原酶类(Quinone Reductases);信号传导(Signal Transduction);空泡(Vacuoles)
DOI
10.1080/15548627.2015.1058683
PMID
26046590
发布时间
2021-06-17
- 浏览52
Autophagy
1063-80页
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文
