换一批MT1-MMP silencing by an shRNA-armed glioma-targeted conditionally replicative adenovirus (CRAd) improves its anti-glioma efficacy in vitro and in vivo.
第一作者：
Ilya,Ulasov
第一单位：
Center for Advanced Brain Tumor Center, Swedish Neuroscience Institute, 550 17th Avenue, Seattle, WA 98122, USA; Laboratory of Experimental Diagnostics and Biotherapy, N.N. Blokhin Cancer Research Center (RONC), Moscow 123481, Russia. Electronic address: ulasov75@yahoo.com.
作者：
医学主题词
腺病毒科(Adenoviridae);老年人(Aged);动物(Animals);脑肿瘤(Brain Neoplasms);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);疾病恶化(Disease Progression);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);遗传载体(Genetic Vectors);神经胶质瘤(Glioma);人类(Humans);羟肟酸类(Hydroxamic Acids);白细胞介素8(Interleukin-8);男(雄)性(Male);基质金属蛋白酶14(Matrix Metalloproteinase 14);小鼠(Mice);中年人(Middle Aged);肿瘤移植(Neoplasm Transplantation);新生血管化, 病理性(Neovascularization, Pathologic);溶瘤病毒疗法(Oncolytic Virotherapy);RNA干扰(RNA Interference);RNA, 小分子干扰(RNA, Small Interfering);移植, 异种(Transplantation, Heterologous);血管内皮生长因子A(Vascular Endothelial Growth Factor A)
DOI
10.1016/j.canlet.2015.06.002
PMID
26052095
发布时间
2019-08-16
- 浏览13
Cancer letters
240-50页
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