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首页> Chemico-biological interactions> In vitro inhibitory activities of six gypenosides on human liver cancer cell line HepG2 and possible role of HIF-1α pathway in them.

In vitro inhibitory activities of six gypenosides on human liver cancer cell line HepG2 and possible role of HIF-1α pathway in them.

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作者： Lin,Shi ^[1] ; Yuzhen,Pi ^[2] ; Cheng,Luo ^[3] ; Chunhong,Zhang ^[2] ; Dehong,Tan ^[4] ; Xianjun,Meng ^[5]

作者单位： College of Food Science, Shenyang Agricultural University, Shenyang 110866, PR China; Department of Emergency Medicine, Laboratory of Rescue Center of Severe Wound and Trauma, PLA, General Hospital of Shenyang Military Command, Shenyang 110016, PR China. ^[1] College of Food Science, Shenyang Agricultural University, Shenyang 110866, PR China. ^[2] Key Laboratory of Food Nutrition and Safety, Ministry of Education, School of Food Engineering and Biotechnology, Tianjin University of Science and Technology, Tianjin 300457, PR China. ^[3] College of Food Science, Shenyang Agricultural University, Shenyang 110866, PR China. Electronic address: linnashi@126.com. ^[4] College of Food Science, Shenyang Agricultural University, Shenyang 110866, PR China. Electronic address: mengxjsy@126.com. ^[5]

关键词 Cytotoxic activity Gynostemma pentaphyllum Gypenosides HIF-1α HepG2

主题词细胞运动(Cell Movement);细胞增殖(Cell Proliferation);细胞存活(Cell Survival);绞股蓝属(Gynostemma);Hep G2细胞(Hep G2 Cells);人类(Humans);缺氧诱导因子1, α亚基(Hypoxia-Inducible Factor 1, alpha Subunit);植物组成部分, 地上(Plant Components, Aerial);植物提取物(Plant Extracts);RNA, 信使(RNA, Messenger);构效关系(Structure-Activity Relationship)

DOI 10.1016/j.cbi.2015.06.004

PMID 26054451

发布时间 2022-04-08

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Chemico-biological interactions

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