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Mutual enhancement of IL-2 and IL-7 on DNA vaccine immunogenicity mainly involves regulations on their receptor expression and receptor-expressing lymphocyte generation.

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第一作者： Yonghong,Zhang

第一单位： Laboratory of Molecular Virology and Immunology, College of Veterinary Medicine, Agricultural University of Hebei, Hebei Engineering and Technology Research Center of Veterinary Biotechnology, Baoding 071000, China.

作者： Yonghong,Zhang ^[1] ; Shuang,Liang ^[2] ; Xiujin,Li ^[3] ; Liyue,Wang ^[1] ; Jianlou,Zhang ^[1] ; Jian,Xu ^[3] ; Shanshan,Huo ^[1] ; Xuebin,Cao ^[4] ; Zhenyu,Zhong ^[5] ; Fei,Zhong ^[6]

作者单位： Laboratory of Molecular Virology and Immunology, College of Veterinary Medicine, Agricultural University of Hebei, Hebei Engineering and Technology Research Center of Veterinary Biotechnology, Baoding 071000, China. ^[1] Department of Medicine, School of Medicine, University of California San Diego, La Jolla, San Diego, CA 92093, USA. ^[2] Department of Biotechnology, College of Environmental and Chemical Engineering, Yanshan University, Qinhuangdao 066004, China. ^[3] Department of Cardiology, 252 Hospital of Chinese PLA, Baoding 071000, Hebei, China. ^[4] Department of Pharmacology, School of Medicine, University of California San Diego, La Jolla, San Diego, CA 92093, USA. Electronic address: z8zhong@ucsd.edu. ^[5] Laboratory of Molecular Virology and Immunology, College of Veterinary Medicine, Agricultural University of Hebei, Hebei Engineering and Technology Research Center of Veterinary Biotechnology, Baoding 071000, China. Electronic address: zhongf@hebau.edu.cn. ^[6]

关键词 DNA vaccine Interleukin-2 Interleukin-7 Mutual effects