换一批MYBL2 guides autophagy suppressor VDAC2 in the developing ovary to inhibit autophagy through a complex of VDAC2-BECN1-BCL2L1 in mammals.
第一作者：
Jia,Yuan
第一单位：
a Department of Genetics; College of Life Sciences; Wuhan University ; Wuhan , China.
作者：
关键词
ATG12, autophagy-related 12ATG16L1, autophagy-related 16-like 1ATG5, autophagy-related 5BAK, BCL2-antagonist/killer 1BCL2, B-cell CLL/lymphoma 2BCL2L1, BCL2-like 1BECN1, Beclin 1, autophagy relatedBeclin1CDS, coding DNA sequenceDpp, days postpartumGATA1, GATA binding protein 1 (globin transcription factor 1)GATA2, GATA binding protein 2LC3B, microtubule-associated protein 1 light chain 3 betaMBS, MYBL2 binding siteMYBL2MYBL2, v-myb avian myeloblastosis viral oncogene homolog-like 2SP1, Sp1 transcription factorVDAC, voltage-dependent anion channelVDAC2ovaryreproductiontranscription regulationwt, wild type
医学主题词
动物(Animals);动物, 基因修饰(Animals, Genetically Modified);动物, 新生(Animals, Newborn);凋亡调节蛋白质类(Apoptosis Regulatory Proteins);自噬(Autophagy);碱基序列(Base Sequence);染色质免疫沉淀法(Chromatin Immunoprecipitation);DNA突变分析(DNA Mutational Analysis);电泳迁移位移试验(Electrophoretic Mobility Shift Assay);女(雌)性(Female);GATA1转录因子(GATA1 Transcription Factor);哺乳动物(Mammals);小鼠(Mice);分子序列数据(Molecular Sequence Data);卵巢(Ovary);启动区, 遗传(Promoter Regions, Genetic);蛋白质结合(Protein Binding);野猪(Sus scrofa);反式激活因子类(Trans-Activators);电压依赖性阴离子通道2(Voltage-Dependent Anion Channel 2);bcl-X蛋白质(bcl-X Protein)
DOI
10.1080/15548627.2015.1040970
PMID
26060891
发布时间
2018-11-13
- 浏览83
Autophagy
1081-98页
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