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A multi-center, open-label trial to compare the efficacy and pharmacokinetics of Artemether-Lumefantrine in children with severe acute malnutrition versus children without severe acute malnutrition: study protocol for the MAL-NUT study.

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第一作者： Lise,Denoeud-Ndam

第一单位： Epicentre, Paris, France. lise.denoeud@epicentre.msf.org.

作者： Lise,Denoeud-Ndam ^[1] ; Alassane,Dicko ^[2] ; Elisabeth,Baudin ^[3] ; Ousmane,Guindo ^[4] ; Francesco,Grandesso ^[5] ; Issaka,Sagara ^[6] ; Estrella,Lasry ^[7] ; Pedro Pablo,Palma ^[8] ; Angeles M Lima,Parra ^[9] ; Kasia,Stepniewska ^[10] ; Abdoulaye A,Djimde ^[11] ; Karen I,Barnes ^[12] ; Ogobara K,Doumbo ^[13] ; Jean-François,Etard ^[14]

作者单位： Epicentre, Paris, France. lise.denoeud@epicentre.msf.org. ^[1] Malaria Research and Training Center, Faculte de Médecine, Pharmacie et d'Odonto-stomatologie, Université des Sciences Techniques et Technologies de Bamako, Bamako, Mali. adicko@icermali.org. ^[2] Epicentre, Paris, France. elisabeth.baudin@epicentre.msf.org. ^[3] Epicentre, Paris, France. ousmane.guindo@epicentre.msf.org. ^[4] Epicentre, Paris, France. francesco.grandesso@epicentre.msf.org. ^[5] Malaria Research and Training Center, Faculte de Médecine, Pharmacie et d'Odonto-stomatologie, Université des Sciences Techniques et Technologies de Bamako, Bamako, Mali. isagara@icermali.org. ^[6] Medecins sans Frontieres, Paris, France. Estrella.Lasry@newyork.msf.org. ^[7] Medecins sans Frontieres, Barcelona, Spain. palma.pp2013@gmail.com. ^[8] Medecins sans Frontieres, Barcelona, Spain. nines.lima@barcelona.msf.org. ^[9] Worldwide Antimalarial Resistance Network (WWARN), Oxford, UK. kasia.stepniewska@wwarn.org.;Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK. kasia.stepniewska@wwarn.org. ^[10] Malaria Research and Training Center, Faculte de Médecine, Pharmacie et d'Odonto-stomatologie, Université des Sciences Techniques et Technologies de Bamako, Bamako, Mali. adjimde@icermali.org. ^[11] Worldwide Antimalarial Resistance Network (WWARN), Oxford, UK. karen.barnes@uct.ac.za.;Division of Clinical Pharmacology, University of Cape Town, Cape Town, South Africa. karen.barnes@uct.ac.za. ^[12] Malaria Research and Training Center, Faculte de Médecine, Pharmacie et d'Odonto-stomatologie, Université des Sciences Techniques et Technologies de Bamako, Bamako, Mali. okd@icermali.org. ^[13] Epicentre, Paris, France. jean-francois.etard@epicentre.msf.org.;TransVIHMI UMI 233, Institut de recherche pour le développement (IRD) - Inserm U 1175 - Montpellier 1 University, Montpellier, France. jean-francois.etard@epicentre.msf.org. ^[14]