The MS Risk Allele of CD40 Is Associated with Reduced Cell-Membrane Bound Expression in Antigen Presenting Cells: Implications for Gene Function.-论文-万方医学网

第一作者： Judith,Field

第一单位： Multiple Sclerosis Division, Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Victoria., Australia.

作者： Judith,Field ^[1] ; Fernando,Shahijanian ^[2] ; Stephen,Schibeci ^[2] ; Australia and New Zealand MS Genetics Consortium (ANZgene) ^[1] ; Laura,Johnson ^[3] ; Melissa,Gresle ^[3] ; Louise,Laverick ^[2] ; Grant,Parnell ^[2] ; Graeme,Stewart ^[2] ; Fiona,McKay ^[4] ; Trevor,Kilpatrick ^[3] ; Helmut,Butzkueven ^[2] ; David,Booth

作者单位： Multiple Sclerosis Division, Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Victoria., Australia. ^[1] Centre for Immunology and Allergy Research, Westmead Millennium Institute, University of Sydney, Sydney, New South Wales, Australia. ^[2] Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Parkville, Australia; Department of Medicine, University of Melbourne, Melbourne, Victoria, Australia. ^[3] Multiple Sclerosis Division, Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Victoria., Australia; Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Parkville, Australia; Melbourne Neuroscience Institute, University of Melbourne, Melbourne, Victoria, Australia. ^[4]

医学主题词青少年(Adolescent);成年人(Adult);老年人(Aged);等位基因(Alleles);B-淋巴细胞(B-Lymphocytes);细胞膜(Cell Membrane);队列研究(Cohort Studies);树突细胞(Dendritic Cells);减量调节(Down-Regulation);女(雌)性(Female);基因型(Genotype);人类(Humans);淋巴细胞活化(Lymphocyte Activation);男(雄)性(Male);中年人(Middle Aged);单核细胞(Monocytes);多发性硬化(Multiple Sclerosis);多态性, 单核苷酸(Polymorphism, Single Nucleotide);RNA, 信使(RNA, Messenger);青年人(Young Adult)

DOI 10.1371/journal.pone.0127080

PMID 26068105

发布时间 2022-03-11

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The MS Risk Allele of CD40 Is Associated with Reduced Cell-Membrane Bound Expression in Antigen Presenting Cells: Implications for Gene Function.

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The MS Risk Allele of CD40 Is Associated with Reduced Cell-Membrane Bound Expression in Antigen Presenting Cells: Implications for Gene Function.

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PloS one

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